A kidney-selective biopolymer for targeted drug delivery

Kidney–targeted drug delivery systems

Kidney-targeted drug delivery systems represent a promising technology to improve drug efficacy and safety in the treatment of renal diseases. In this review, we summarize the strategies that have been employed to develop kidney-targeted drug delivery systems. We also describe how macromolecular carriers and prodrugs play crucial roles in targeting drugs to particular target cells in the kidney...

Biopolymer based nanosystem for doxorubicin targeted delivery.

This study describes formation of an actively and passively targeted, water-soluble drug delivery system (DDS) which contains doxorubicin (DOX). The system comprises two biocompatible and biodegradable polymers: poly-γ-glutamic acid (PGA) and chitosan (CH). Self-assembly of these biopolymers in aqueous medium results stable nanoparticles (NPs) with a hydrodynamic size of 80-150 nm and slightly ...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Biopolymer-Based Nanoparticles for Drug Delivery

................................................................................................................................ i Acknowledgements .............................................................................................................. ii List of original publications ................................................................................................ iv Abbre...